MCNV2 Toolbox
Welcome to the MCNV2 documentation. MCNV2 is a technology-agnostic toolbox for CNV quality assessment using Mendelian Precision in parent–offspring trios.
Note
This documentation covers both the interactive Shiny application and the command-line interface (CLI) for batch processing.
Getting Started
Installation
Install MCNV2 (R + Python) and validate your environment.
Quickstart
Run your first Mendelian Precision analysis in minutes.
Tutorials
Shiny Tutorial
Interactive exploration: filters, plots, exports.
CLI Tutorial
Batch runs, reproducible pipelines, and wrappers.
Core Concepts
Mendelian Precision — Understand the MP metric
Inheritance status — Inheritance status calculation
Filtering strategies — Quality filters and their impact